And can you then supervice me and help me choose a herb protocoll when the results are here? Lyme can live outside of cells and inside of cells. It is a very good source of resveratrol, and most benefits of Japanese Knotweed may actually just be benefits of resveratrol. I am so sorry. ), overwhelming feelings of depression and anxiety justdont go away. I remember you said you do tennis and athletics and I was hanging on your recovery..so you give me hope believe it. Each of these herbal medicine options is shown in lab experiments to treat growing and persister phases of Lyme. The following article describes how to use Japanese Knotweed extract (Scientific name of plant Fallopia Japonica) for treating Lyme disease. 2019;8(2):72. doi:10.3390/antibiotics8020072(, Ma X, Leone J, Schweig S, Zhang Y. Botanical medicines with activity against stationary phase Bartonella henselae. This is also a pulse-dose regimen (see below under Special Considerations). Generally, I suggest rotating a prescription antibiotic every six months to prevent resistance to that antibiotic. 2023 Healthline Media UK Ltd, Brighton, UK. Here is a list of prescription medications shown in human experiments to help with persister Lyme. Antibiotics (Basel). Theory and observation show us that combinations of antimicrobials work better than single agents alone. The taller ones are covered by tough rind that must be first peeled off before consumption. Richard Horowitz, MD has promoted the use of dapsone-based regimens to treat both Lyme and Bartonella persisters. Its also one thats used very often for Bartonella infections, and it has a naturally occurring constituent known as resveratrol. Aspire. Youyou Tu: Significance of winning the 2015 Nobel Prize in Physiology or Medicine. Med., 21 February 2020. THE CORE BUHNER PROTOCOL FOR BARTONELLA INFECTIONS: Japanese knotweed root tincture (cytokine cascade reduction and endothelial cell protection) , 1/4-1/2 tsp 3x daily For some, this may mean they achieve complete recovery; for others, it may not. Many physicians have different ways of pulsing antibiotics. Polygonum cuspidatum (Japanese knotweed) . I do not use essential oils as the only treatment for Lyme but it might be a nice adjunct to therapy to herbals. http://aspire.care/featured/overview-of-lyme-tick-borne-illness/ You can dose this frequently (up to every 10 minutes) if need be. I am ready to pay a visit to our sons Vet for a diagnosis his dog was diagnosed with Lyme Disease, and our woods was pretty much the only place he could have gotten it from. He has all of the above bacteria, and inflammation through out his body , and also experiences chronic ringing in his ears about 8 or 9 out of ten. (In "Healing Lyme"Buhner explains . In other preclinical studies, it has been found to have anti-tumor and anti-inflammatory effects and protect the nervous system and heart. Published July 2010. Next, they looked at doxycycline combined with Baicalein, which is the active constituent in Chinese Skullcap. You can read more details about how to take both regimens in: In my experience, I find the prescription antibiotic combinations below work 85-90 percent of the time. It has all kinds of good effects on the body, acting as an antbiotic, reducing inflammation,. It supports the innate immune function to react to the infection caused by the Lyme disease. I take it because I trust Buhner's take on treating lyme and I've made good progress following his protocol. Cytokines are the part of the immune system that lead to the inflammation seen in Bartonella infections. This herbal medicine is traditionally used to treat Babesia and malaria. Japanese Knotweed (Fallopia japonica, or You Ji Hu Zhang in Chinese) is native to eastern Asia. Based on Horowitz experiments and my use of the medication with my patients, I find improvements of 20 percent or so in those that can tolerate the treatment. It found multiple herbals that are safe and have potential potent antimicrobial benefits against the persister form of Borrelia burgdorferi. Japanese Knotweed, a bamboo resembling (although, not related) large plant species is native to Eastern Asia, including countries like, Japan, Korea and China. Because of this, I only use disulfiram alone to treat Lyme when these other germs are not active. It supports the innate immune function to react to the infection caused by the Lyme disease. When Lyme is attacked, it goes into cyst form so that it cannot be killed off. The researchers pitted each of these plant extracts against free-swimming (planktonic) B. burgdorferi and microcolonies of this bacterium aggregates of bacterial cells. It also turns urine and stool blue and is very hard to scrub off porcelain toilets. The Buhner/Rawls combination helps about 60-65 percent of the time in my clinical observations. With this binder, you want to give it two hours away from any other medications or supplements as it will bind to them and draw them out of the body. Treating Borrelia, the Lyme germ, with antibiotics is complicated because limited research shows which treatment regimens work best. Resveratrol could help with the cardiovascular impact of Lyme. Also, it is also anti-microbial, protects the central nervous system, clears out endotoxins, anti oxidant, and is . They found the combination of doxycycline and Baicalein provided the additional benefit of being able to attack the latent, rounded form, not just the active dividing spirochete form of Borrelia. I have known people who buy the powdered herb and put it in capsules or create a tincture by soaking it in alcohol. It has been used in traditional medicine for the treatment of malaria, TB, hepatitis, and septicemia. Lyme can go into persister form so you can have symptoms that relapse and remit. It was named after Lyme, Connecticut, where a number of people were suffering from arthritis and inflammatory symptoms. I'm not sure what's going on with me. In some countries, the Japanese Knotweed is considered as an invasive species but it does have its uses. Japanese knotweed tincture high levels of resveratrol make this an important part of treatment. Cryptolepis can treat persister and growing Lyme. Resveratrol is also found in red grapes, berries, peanuts, etc. My body didn't like more than that. He researched both a 100 mg dapsone protocol and a 200 mg dapsone protocol. Wild fora. doi:10.2147/DDDT.S101486(, Pothineni VR, Potula H-HSK, Ambati A, et al. I am obviously not having a heart attackha, ha, ha.. There is a Babesia Buhner protocol .you know that right? In two different studies in 2021, however, Dr. Zhang and colleagues have shown Cryptolepsis is effective at treating growing and persister forms of Bartonella and Lyme. This study provides the first convincing evidence that some of the herbs used by patients, such as Cryptolepis, black walnut, sweet wormwood, cats claw, and Japanese knotweed, have potent activity against Lyme disease bacteria, especially the dormant persister forms, which are not killed by the current Lyme antibiotics, says study co-author Prof. Ying Zhang. It was first described with the use of penicillin treatment for syphilis. They are all in glycerin form, so they taste better are more tolerated by children. Suggested dosage: 200-800 mg Japanese knotweed (standardized to 50% trans-resveratrol) two to three times daily. Top on the list was Cryptolepis, behind that Japanese knotweed, cat's claw, Chinese skullcap, artemisia, black walnut, Cistus incanus, which is actually more of an essential oil, Andrographis, stevia, grapefruit seed extract, and monolaurin. Which Essential Oil Is Best for Anxiety and Depression. All rights reserved. Townsend Letter. Longer-term use could be months or years, depending on the severity of the illness. I usually start with Japanese Knotweed and my Cats Claw. Gives the rest of us hope. So would the Japenese knotweed and Cats claw work for animals too? A Miracle Antibiotic? He is a member of the International Lyme and Associated Disease Society (ILADS), The Institute for Functional Medicine, and The American Academy of Anti-Aging Medicine. Since Borrelia adapts for self-protection and two-weeks of antibiotics is often not sufficient, exploring herbals provides some additional ways to treat Lyme disease. These are some commonly used herbs for Lyme disease, and they tested each one. Artemisia, also known as sweet wormwood, has been used medicinally for over 2000 years. It is important to understand what a Herxheimer or Die Off reaction is and how to mitigate it. The whole flowering plant is used to make medicine. The dapsone is included here to treat persisters. CYTOKINE REMODULATION Important compound in Japanese Knotweed. Source: In Vitro Effectiveness of Samento and Banderol Herbal Extracts on the Different Morphological Forms of Borrelia Burgdorferi. Before I describe herbal and prescription antibiotic approaches I find helpful treating Lyme in my Seattle practice, lets talk about terms. Study 2: Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi, Source: Feng Jie, Leone Jacob, Schweig Sunjya, Zhang Ying Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. Treatments include antimicrobials that address persisters, in addition to the growth phase. 2 g x 4/day to 3.8 . Japanese Knotweed Root The most important herb to use is Japanese knotweed root ( Polygonum cuspidatum ). In fact, just one 7-day treatment with 1% Ghanaian quinine extract was able to eradicate the bacterium in lab dishes. Therefore, the plan that follows is notand cannot bea complete or comprehensive guide. Next is Cryptolepis is definitely becoming one of my favorite herbals to be used for my PANS kids. Of the various herbal options to treat persisters, this is my go-to herbal anti-microbial based on benefits I see in my practice. It is by no means comprehensive. I use hooftinder polypore in this which also is good in Lyme treatment. That is just suggested as a range. The next is Burber Panella, part of the Cowden Protocol. Brilliant, informative article. Some other herbs or drugs can also be consumed along the knotweed to enhance the medication required for the proper removal of Lyme causing bacteria. I encourage everyone to look into the cell danger response that Bob Navieux has been working, which essentially shows that the mitochondria are important for the immune system. This herb has a long history of use in Africa for malaria, and has been used in the Lyme community to help treat the co-infection . Two tablets per day. Inflammation can occur through a number of different pathways in the body but the root of this plant is specific for the exact pathways that the Lyme bacteria initiate. These treatment regimens deliver effective drug levels that penetrate tissues and the brain. I was only taking 1 200mg a day and I started taking 400 3x a day and I am having a very bad neuro herx that I can't stop with my normal methods. The products are going to be taken daily with the set schedule that you work on with the practitioner. Knotweed is used for swelling ( inflammation) of the main airways in the lung ( bronchitis ), cough, sore throat, a mild . The herbal combination options help 85-90 percent of the time. DD is no longer herxing so 2 grams 3x daily is where we remain. Pulsing herbal antibiotics does not work well; therefore, I do not recommend it here. I will not be talking further about iodine since the focus of this article is on herbs specifically. Source: Feng Jie, Zhang Shuo, Shi Wanliang, Zubcevik Nevena, Miklossy Judith, Zhang Ying. Forms - Japanese Knotweed can be found as powders, tablets, decoction, teas, fortified wines, tinctures, capsules and other forms. A lot of PANS kids will be sensitive to viruses, meaning that they will have flares when they come into contact with viruses. Before I dive into how you can starttreating Lyme bacteria with Japanese Knotweed, lets have a closer look atwhat Lyme disease is: Lyme disease is an infectious disease caused by species of bacteria from the genus Borrelia. It is one of my favorite herbs to use. About 90 percent of the time when antibiotics are started or changed during a treatment, a person will initially worsen. This new study came out in February 2020. The cryptolepis and the Cats Claw can treat persister and growing Lyme. Inside of cells, Lyme exists without a cell covering known as an L-form. Lyme Disease: Japanese Knotweed root is known to aid the central nervous system and kill Lyme bacteria. . This is an average. It is also compounded as a 62.5 mg pill. But did you know that Japanese knot weed could be more effective than antibiotics at tackling the growing problem of Lyme disease? Its been shown to reduce short-term memory impairment when its combined with IV ceftriaxone in patients with Lyme disease. Macrolides (like clarithromycin) and tetracyclines (like doxycycline), work in the intracellular and extracellular spaces. This plant can be used in either tincture or capsule form and is quite useful in treating Lyme . Subscribe to receive our FREE pdf download book: How to Successfully Treat Lyme: Key Info before You Treat or Treat Again & The Ross Lyme Support Protocol; health tips; updates; special offers; and more. When Will I Start to Feel Better? In my view, for those with weakened digestive fire, a lot of capsules tends to create a gluey substance, and possibly more Ama, or toxic residues). 500 mg of amoxicillin is a very high dose, which is four times stronger than physicians prescribe for other infections, such as ear infections. Dr. Lindsey Wells is a naturopathic physician. 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