Pharmacogenomics of human OATP transporters. View abstract. 1995;15(8):465-467. Medications that cause sleepiness and drowsiness are called sedatives. B., Blach-Olszewska, Z., and Aliev, G. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? Int J Cancer 9-10-2003;106(4):559-565. Huang, Y., Tsang, S. Y., Yao, X., and Chen, Z. Y. Kang, T. H., Hong, B. N., Park, C., Kim, S. Y., and Park, R. Effect of baicalein from Scutellaria baicalensis on prevention of noise-induced hearing loss. Use of this Web site does not create an expressed or implied physician-patient relationship. View abstract. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. Shih, H. C., Hsu, C. S., and Yang, L. L. In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. Morgan SL, Baggott JE, Moreland L, et al. This could increase how much lithium is in the body and result in serious side effects. May Help Fight Cancer Cells. View abstract. Protective effect of baicalein extracted from Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice. 2007;56(6):280-283. Yeh J.H, Chiu H.F, Wang J.S., and et al. Taking Baikal skullcap along with diabetes medications might cause blood sugar to drop too low. Talk with your healthcare provider before using Baikal skullcap if you are taking medications used for lowering cholesterol. Kong XT, Fang HT, Jiang GQ, et al. Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation. View abstract. Vopr.Onkol. View abstract. This will help them manage your care and keep you safe. Zhongguo Zhong.Yao Za Zhi 2001;26(11):768-769. CNS.Neurol.Disord Drug Targets. WebThe root of Scutellaria baicalensis is used as medicine. J Med Food 2007;10:442-51. J Ethnopharmacol. Planta Med 2000;66:91-3. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Hong, T., Jeong, M. L., Zahn, M., Fay, B. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. Immunopharmacology 2000;49:295-306. Taking Baikal skullcap along with medications that also slow clotting might increase the chances of bruising and bleeding. Ceska.Slov.Farm. Zhongguo Zhong.Yao Za Zhi 2010;35(6):682-685. Martin, J. and Dusek, J. Neuroprotective effects of flavonoids were ameliorated by diazepam, a GABA receptor agonist, suggesting that the components influence GABA receptor activity(5). 1-8-2007;245(1-2):269-274. View abstract. Fan L, Zhang W, Guo D, et al. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. A Scutellaria Baicalensis Root Extract trade name mixture (30% ethanol extract) is reported to contain flavonoid compounds. The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1. Eur J Pharmacol 7-1-2011;661(1-3):124-132. View abstract. (Elite.Ed) 2010;2:1538-1547. Adv Ther 2010;27:731-42. Planta Med 2011;77(5):455-460. A., Sherstoboev, E. Y., Zueva, E. P., Razina, T. G., Amosova, E. N., and Krylova, S. G. Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma. View abstract. View abstract. Eksp.Klin Farmakol. View abstract. Huang, R. L., Chen, C. C., Huang, H. L., Chang, C. G., Chen, C. F., Chang, C., and Hsieh, M. T. Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis. 5-17-2011;135(2):359-368. Baikal skullcap can also affect most peoples blood sugar levels, but people with diabetes can get negative results with the herb. Therapeutic Research Faculty 2020. Skin contact Rinse skin with water/shower. Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. Planta Med 1998;64:571-2. Baikal skullcap (Scutellaria baicalensis) is a plant native to China and Korea. Typical doses (see individual product information): Dried herb: 1 to 2 g 3 times/day; Tea: 240 mL 3 times/day (pour 250 mL of boiling water over 5 to 10 mL of the dried herb and steep for 10 to 15 minutes); Tincture: 2 to 4 mL 3 times/day. Vitamin D Deficiency: How Much Vitamin D Is Enough? The dose of your diabetes medication might need to be changed. Naunyn-Schmiedeberg Arch Pharmacol 2006;372:432-43. View abstract. Ye F, Wang H, Jiang S, et al. This Chinese herb may slow down blood clotting, increasing the risk of bleeding and bruising in people who already have some bleeding disorders. View abstract. Cancer Treat Rev 2009;35(1):57-68. Stop using Baikal skullcap at least 2 weeks before a scheduled surgery. Clin Transl Sci 2021;14(5):2017-2024. View abstract. Drug Metab Dispos 2005;33:537-46. WebSummary: As a traditional Chinese herbal medicine, Scutellaria baicalensis has shown significant effects on the treatment of various diseases, especially hepatitis, diarrhoea, vomiting and high blood pressure. Baikal skullcap might lower blood sugar levels. Laboratory studies have shown S. barbata can limit the growth of cancer cells. To avoid any View abstract. View abstract. [Study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. Analysis of essential oils from different organs of Scutellaria baicalensis. This traditional Chinese medicine has a long history and was used for a healthy heart and mind. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. Am J Chin Med 2001;29(1):69-81. View abstract. Food Chem Toxicol. Song, S. J., Li, F. F., Xu, Y., Zhang, L. H., Yuan, F., and Zhang, Y. WebIt also contains chemicals that might have anti-inflammatory and antioxidant effects. [The Baikal scullcap (Scutellaria baicalensis Georgi)--a potential source of new drugs]. Gao, J., Morgan, W. A., Sanchez-Medina, A., and Corcoran, O. Pharmacol.Res. Shang, Y. Am J Chin Med 2011;39(4):693-704. Hao, H., Aixia, Y., Dan, L., Lei, F., Nancai, Y., and Wen, S. Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. Lai, M. Y., Hsiu, S. L., Chen, C. C., Hou, Y. C., and Chao, P. D. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Eur J Pharmacol 4-24-2006;536(1-2):192-199. Kimura, Y., Matsushita, N., and Okuda, H. Effects of baicalein isolated from Scutellaria baicalensis on interleukin 1 beta- and tumor necrosis factor alpha-induced adhesion molecule expression in cultured human umbilical vein endothelial cells. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. Am J Chin Med 2006;34(2):245-261. Zhongguo Ying.Yong.Sheng Li Xue.Za Zhi 2009;25(3):344-348. Furthermore, this herb has not been treated alone on cancer cells, but it showed results when combined with other herbs and medicines. The pharmacology of Chinese herbs. Biol Pharm Bull 2011;34(5):727-733. Zhang CZ, Wang SX, Zhang Y, et al. ]. View abstract. Diabetes: Baikal skullcap can affect blood sugar levels in people with diabetes. Baikal skullcap is used to treat respiratory infections, hay fever, and fever. View abstract. Select a condition to view a list of vitamins. 2005 - 2023 WebMD LLC, an Internet Brands company. View abstract. Have a cup of it daily. Scutellaria baicalensis root extract is also a very potent tyrosinase inhibitor. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. This is especially relevant to macrophages and immune cells. View abstract. J Med Chem 10-21-2004;47(22):5555-5566. View abstract. Cancer Lett. Ann Intern Med 2012;156:857-60. Chen, L. G., Hung, L. Y., Tsai, K. W., Pan, Y. S., Tsai, Y. D., Li, Y. Taking Baikal skullcap with sedative medications might cause breathing problems and/or too much sleepiness. Zhang CZ, Wang SX, Zhang Y, et al. View abstract. View abstract. Orzechowska B, Chaber R, Wisniewska A, et al. Call us at 833-347-1665 to make an appointment. Pharmacol Res 2001;43(2):173-178. View abstract. Takahashi, H., Chen, M. C., Pham, H., Angst, E., King, J. C., Park, J., Brovman, E. Y., Ishiguro, H., Harris, D. M., Reber, H. A., Hines, O. J., Gukovskaya, A. S., Go, V. L., and Eibl, G. Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity. Planta Med 2001;67(4):331-334. Chemicals in skullcap might cause sleepiness. View abstract. This will help them manage your care and keep you safe. View abstract. Chang, H. H., Yi, P. L., Cheng, C. H., Lu, C. Y., Hsiao, Y. T., Tsai, Y. F., Li, C. L., and Chang, F. C. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. View abstract. Chemicals in skullcap might cause sleepiness. 2020;318(1):E52-E61. View abstract. This will help them manage your care and keep you safe. View abstract. Baikal Scullcap, Baikal Skullcap Root, Chinese Skullcap, Escutelaria Asiatica, Huang Qin, Huangquin, Hwanggum, Ogon, Ou-gon, Racine de Scutellaire du Lac Bakal, Radix Scutellariae, Scullcap, Scute, Scutellaire, Scutellaire Chinoise, Scutellaire du Lac Bakal, Scutellaria, Scutellaria baicalensis, Scutellaria macrantha, Scutellariae Radix, Skullcap, Wogon. Zhongguo Zhong.Yao Za Zhi 2009;34(22):2910-2915. Your lithium dose might need to be changed. View abstract. Planta Med 2000;66:70-1. reduce wrinkles, smooth skin) but without the side effects (though it seems now that the INCI name of Lanablue was Use of this Web site does not create an expressed or implied physician-patient relationship. View abstract. Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others. View abstract. Copyright 2023 by RxList Inc. An Internet Brands company. Eur J Drug Metab Pharmacokinet. Arjmandi BH, Ormsbee LT, Elam ML, et al. View abstract. View abstract. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. Monitor your blood sugar closely. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. View abstract. Animal models also suggest antitumor activity with S. barbata across a range of cancers(16)(17)(18)(19)(20). Afr J Tradit.Complement Altern Med 2010;7(4):339-349. Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Concentration-dependent inhibitory effects of baicalin on the metabolism of dextromethorphan, a dual probe of CYP2D and CYP3A, in rats. J Biol Chem 9-1-2000;275(35):27466-27472. 7-28-2004;211(1):39-46. View abstract. View abstract. J Nat Prod 1997;60(6):598-601. Krakauer, T., Li, B. Q., and Young, H. A. Biol Pharm Bull 2004;27(10):1580-1583. View abstract. In vitro studies suggest that S. barbata has antibacterial(1), antioxidant(15), antimutagenic(2), and anticancer(3)(4)(5)(6)(7)(8)(10)(11)(12) properties. In that case, it is either used for hormone synthesis or hormone breakdown, including estrogen and testosterone, which are not advised to combine with the Chinese herb. Suppressive effect of wogonin on mite antigen-induced TARC expression. PC-SPES (PDQ) - Health Professional Version. The ethyl acetate (EtOAc) extract showed high ROS scavenging ability, and four compounds were subsequently isolated and purified from this extract: baicalin, View abstract. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. Wang R.T, Zhang J.X, and Dong Y.J. View abstract. This study reports three major findings: (1) S. baicalensis has a potent inhibitory effect Protective effect of scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by injection A25-35. Mol Biol (Mosk) 2009;43(6):1082-1087. View abstract. Zhongguo Zhong.Yao Za Zhi 2007;32(17):1827-1829. View abstract. The extract coming from the bark of the White Willow, a big (25 m/80 ft.) tree that likes to live on riverbanks. A., Sherstoboev, E. Y., Zueva, E. P., Razina, T. G., Amosova, E. N., and Krylova, S. G. Effect of baikal skullcap extract administered alone or in combination with cyclophosphamide on natural cytotoxicity system in mice with Lewis lung carcinoma. [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. View abstract. WebScutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. 6-29-2011; View abstract. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. 2009;29(1):211-213. Mol Urol. Lee, C. Y., Wang, J. Y., Chen, T. C., Jiang, J. K., Peng, C. H., Kuo, C. D., Chang, W. C., Chiu, J. H., and Wu, C. W. Effects of S/B remedy containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on hepatic interleukin-6 related signal transducer and activator of transcription 3 activation in mice through cell-cell interaction. It is also effective against some bacteria. In Vivo 2004;18(4):497-503. View abstract. Intern Med J. The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. 2-1-2010;84(2):137-144. View abstract. View abstract. 11-15-2009;171(1-3):508-513. Sonoda, M., Nishiyama, T., Matsukawa, Y., and Moriyasu, M. Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. View abstract. View abstract. Cancer Res 7-15-2003;63(14):4037-4043. Yin, F., Liu, J., Ji, X., Wang, Y., Zidichouski, J., and Zhang, J. Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Abeta aggregation in SH-SY5Y cells. Wu, J. Dong R, Li L, Gao H, et al. View abstract. Lee, S., Kim, D. H., Jung, J. W., Oh, J. H., Park, H. J., Park, C., Huh, Y., Cheong, J. H., Oh, T. H., and Ryu, J. H. Schizandra chinensis and Scutellaria baicalensis counter stress behaviors in mice. Advances of wogonin, an extract from Scutellaria baicalensis, for the treatment of multiple tumors. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. View abstract. Regulska-Ilow, B., Biernat, J., Grajeta, H., Ilow, R., and Drzewicka, M. Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on the level of serum lipids, and the development of laboratory rats fed with fresh and oxidized fats. J Ethnopharmacol 2005;98:295-300. Monitor your blood sugar closely. Rosenbaum, C. C., O'Mathuna, D. P., Chavez, M., and Shields, K. Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis. J Nat Prod 1998;61:1413-5. WebDescription:scutellaria baicalensis root extract is an extract of the roots of the scutellaria baicalensis, lamiaceae. Chromatographic fingerprint and quantitative analysis of seven bioactive compounds of, Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of, Using the gene expression signature of scutebarbalactone VN isolated from. Dosage: 39 g/day/adult. Low blood pressure: Baikal skullcap might lower blood pressure. Onco Targets Ther 2016;9:2935-43. Scutellaria is multi-functional: antioxidant, anti-inflammatory, and antithrombic agent, as well as neuroprotectant Scientific and clinical relevance to the fact is not determined, but it is better to stay on the safer side. Baikal skullcap (scientific name Scutellaria baicalensis) is a plant. Toxicol.Appl.Pharmacol 8-1-2011;254(3):221-228. View abstract. 2000;4(3):289-291. 73.^ Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion Baumann, S., Fas, S. C., Giaisi, M., Muller, W. W., Merling, A., Gulow, K., Edler, L., Krammer, P. H., and Li-Weber, M. Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. Leung, H. W., Yang, W. H., Lai, M. Y., Lin, C. J., and Lee, H. Z. Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. Levy RM, Khokhlov A, Kopenkin S, et al. December 19, 2017. Nontoxic; LD 50 is tested, none. Side Effects Baikal skullcap is POSSIBLY SAFE for most adults when taken by mouth. Anesth Analg 2003;97:1724-9. J Ethnopharmacol. J Cell Biochem 10-1-2010;111(2):274-283. Burnett BP, Jia Q, Zhao Y, Levy RM. Chen, Y., Lu, N., Ling, Y., Gao, Y., Wang, L., Sun, Y., Qi, Q., Feng, F., Liu, W., Liu, W., You, Q., and Guo, Q. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, Integrative Medicine at Home Membership Program. WebAbstract This study was carried out to investigate the antifibrotic effects of methanol extracts from the traditional Chinese medicinal herb, the root of Scutellaria baicalensis Georgi, on liver fibrosis induced by bile duct ligation and scission Keep in mind that natural products are not always necessarily safe and dosages can be important. Chen et C. Ling and Scutellaria baicalensis Georgi. Food Chem Toxicol. View abstract. View abstract. Go, W. J., Ryu, J. H., Qiang, F., and Han, H. K. Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. Planta Med 2010;76(1):76-78. View abstract. It is not an approved drug. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. Zhong.Yao Cai. Ann Intern Med 2012;156:857-60. View abstract. [Flavonoids from Scutellaria baicalensis and their bioactivities]. Huang, W. M., Yan, J., and Xu, J. From: Polyphenols in Human Health and Disease, 2014. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. Fu, J., Cao, H., Wang, N., Zheng, X., Lu, Y., Liu, X., Yang, D., Li, B., Zheng, J., and Zhou, H. An anti-sepsis monomer, 2',5,6',7-tetrahydroxyflavanonol (THF), identified from Scutellaria baicalensis Georgi neutralizes lipopolysaccharide in vitro and in vivo. Morgan SL, Baggott JE, Morel, L, Desmond R, and Kendrach AC. Intern Med 2001;40:764-8. Discover the Health Benefits of Mushroom Extracts, Harnessing the Power of Grape Seed Extract for Health Benefits, The Health Benefits of Yohimbe Bark Extract, The Benefits of Leaf Extract: How This Natural Remedy Can Improve Your Health, Understanding Food Grade Tannic Acid: Its Role in Food and Health. With cancer, where you get treated first matters. Cancer Sci 2008;99(4):689-695. View abstract. Zhang, K., Lu, J., Mori, T., Smith-Powell, L., Synold, T. W., Chen, S., and Wen, W. Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway. Therefore, if you are a diabetic patient, you should stay away from such herbs. View abstract. Phytother.Res 2003;17(6):640-644. Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics. Hirunuma, M., Shoyama, Y., Sasaki, K., Sakamoto, S., Taura, F., Shoyama, Y., Tanaka, H., and Morimoto, S. Flavone-catalyzed apoptosis in Scutellaria baicalensis. Wu X, Zhang H, Salmani JM, et al. View abstract. View abstract. Cancer Lett. View abstract. View abstract. Details. From diagnosis to treatment, our experts provide the care and support you need, when you need it. View abstract. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Biochim Biophys Acta 1999;1472:643-50. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Gol'dberg VE, Ryzhakov VM, Matiash MG, et al. Scheck, A. C., Perry, K., Hank, N. C., and Clark, W. D. Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. Lixuan, Z., Jingcheng, D., Wenqin, Y., Jianhua, H., Baojun, L., and Xiaotao, F. Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models. Larger studies in humans that test safety and effectiveness are needed to determine under what circumstances S. baicalensis may be beneficial. Porterfield, H. UsToo PC-SPES surveys: review of studies and update of previous survey results. Scutellaria baicalensis is a very well-known anti-inflammatory agent widely used in oriental medicine. Tyrosinase is a key enzyme involved in the synthesis of melanin, the pigment that gives skin color. View abstract. Planta Med 1995;61(2):150-153. It can cause drowsiness, fever, lung inflammation, and other information View abstract. View abstract. Different extracts of this herb have been found to kill cancer cells in the body, but human research is pending in this field. CNS.Neurol.Disord Drug Targets. Li L, Gao H, Lou K, et al. View abstract. View abstract. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. View abstract. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban. View abstract. Extracts were added in the amount of 2.0 g/100 g of meat batter. B., and Chun, M. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. Check your mobile for SMS (Didn't get the message, repeat Step 1). It is often used in combination with other herbs. WebScutellaria Baicalensis Extract. View abstract. J Ethnopharmacol. View abstract. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. Ye, F., Jiang, S., Volshonok, H., Wu, J., and Zhang, D. Y. Molecular mechanism of anti-prostate cancer activity of Scutellaria baicalensis extract. Some cancer cell lines undergo cell death when exposed to extracts of this herb, but some compounds in this herb may actually have opposite effects. View abstract. Consult your Doctor if you are Pregnant and Breastfeeding. Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others. Baikal skullcap might have an effect like a water pill or "diuretic." Baikal skullcap might also cause sleepiness and drowsiness. Toxicology 5-2-2009;259(1-2):10-17. View abstract. Liu, J. J., Huang, T. S., Cheng, W. F., and Lu, F. J. Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation. Bull Exp Biol Med 2004;137(5):471-474. US Food and Drug Administration (FDA). Typical doses (see individual product information): Dried herb: 1 to 2 g Altern.Ther.Health Med. It is not an approved drug. Clin Cancer Res 5-15-2005;11(10):3905-3914. Nutr Res 2009;29:298-304. Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer. First-aid measures Inhalation Move to fresh air. Tseng, Y. P., Wu, Y. C., Leu, Y. L., Yeh, S. F., and Chou, C. K. Scutellariae radix suppresses hepatitis B virus production in human hepatoma cells. Scutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. Heo, Y. M., Heo, Y. M., Yan, J., kim, M. 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